Alkylation of Galactosyl, Mannosyl and Lactosyl Barbiturate

Authors

  • G J Clarkson Chemistry Department, University of Warwick. U.K.
  • C A Adah Chemistry Department, Benue State University, Makurdi.

DOI:

: https://doi.org/10.46912/napas.13

Keywords:

Alkylation, galactosyl, mannosyl, actosyl barbiturates

Abstract

The reactions of galactosyl, mannosyl and lactosyl barbiturates with 4-benzyloxybenzyl chloride and á- halo amide with galactose barbiturate were investigated. The products (benzyloxybenzyl-galactosyl barbiturate, benzyloxybenzyl-mannosyl barbiturate, benzyloxybenzyl-lactosyl barbiturate and galactose amide) were characterised by high field nuclear magnetic resonance spectroscopy, mass spectrometry, carbon, hydrogen and nitrogen combustion analyses and further characterised as per- acetate. The alkylation or the barbituric salts proceeds well with the electrophiles and are routes to novel C-glycosyl lectin binders.

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Published

2015-12-28

How to Cite

Clarkson, G. J., & Adah, C. A. (2015). Alkylation of Galactosyl, Mannosyl and Lactosyl Barbiturate. NIGERIAN ANNALS OF PURE AND APPLIED SCIENCES, 6, 91–98. https://doi.org/10.46912/napas.13

Issue

Vol. 6 (2015)

Section

Original Article